Thursday, May 18, 2017

AstraZeneca sues exec Luke Miels after his defection to GlaxoSmithKline

GlaxoSmithKline's poaching of pharma industry veteran Luke Miels from AstraZeneca in January was billed as an early win success for incoming CEO Emma Walmsley, who scrambled to replace global pharma president Abbas Hussain and other departing execs.

Fast-forward to the present, and the appointment has opened a can of worms. Bloomberg reported that Miels is currently on "gardening leave" from AZ after facing a lawsuit from his current employer alleging breach of employment.

AZ wants Miels to honor the terms of the contract he signed as executive VP of its European pharma business and has taken to the courts to try to force him to do so, according to the newswire.

Intellia moves closer to clinic with CRISPR tech

Intellia Therapeutics has taken another step toward human trials of its gene editing technology after reporting new data in animal models.

The CRISPR specialist says it has been able to show for the first time that it is able to not only achieve long-term suppression of a gene using its gene-editing CRISPR/Cas9 drug, in this case the sequence coding for serum transthyretin (TTR) protein, but also demonstrate a dose-dependent reduction in the activity of the target gene in a second animal species.

New data from studies in mice show that a previously reported 97% reduction in TTR—driven by 70% gene editing efficiency working in mouse livers—lasts for up to six months from a single dose. Meanwhile, a study in rats showed a similar dose-dependent reduction in the TTR gene, and crucially evidence of comparable activity in a second species as Intellia builds the case to move to the clinic.

Biotech pioneer and former Genzyme CEO Henri Termeer dies

The biotech industry is mourning the loss of one of the sector's founding fathers after the death of Genzyme founder Henri Termeer at the age of 71.

According to the Boston Globe, Termeer died after collapsing at his home in Marblehead, Massachusetts, on Friday night.

Termeer was at the helm of Genzyme for nearly 30 years, joining the company in 1983 and rising quickly to the role of CEO before it was acquired by Sanofi in 2011 for more than $20 billion. He is credited with not only transforming the small company into one of the world's leading biotech companies but also playing a leading role in working out how to develop a business model that opened up the market for rare and orphan disease therapies—to the benefit of patients and shareholders alike.


Biotech pioneer and former Genzyme CEO Henri Termeer dies

Thursday, May 11, 2017

Prof. Dr. M. Amjad Hossain: Make your Appointment in Hotline

Prof. Dr. M. Amjad Hossain
MBBS, MS (Ortho)
Arthoplasty and trauma surgeon
President Bangladesh Orthopaedic Society
Former Professor & Head Orthopaedic Surgeon
Dhaka Medical College & Hospital
Chief Consultant
Orthopaedic Surgery Dept
Lab Aid Arthroplasty Center
Labaid Hospital Ltd,
Dhanmondi, Dhaka-1205.
Contact number: + 8801711530611

Best Practice to make your Appointment for Prof. Dr. M Amjad Hossain. Dr. Amjad hossain is the leading leader & expert Ortho Surgery across the country. 

It is little bit difficult to get appointment to him. Currently, HOTLINE is managing all the appointment behalf of LABAID HOSPITAL LTD. 

How make Appointment

# Dial Hotline 10606 the day before you wish to make Appointment

# Start Calling from couple of Mobile phone from 10:55 am.

# Hotline number is busy always. And it may take only 2 mint for Hotline to record appointment for Dr. Amjad Hossain. Because hotline has many desk and the call automatically distribute to several Desk and many of customers service agent offer appointment at a time. 

# So if you hear the voice that number is busy now. Do not cut the line. Stay connected in the line continue. When the call finished then re-dial immediately again. 

# If you try from a single number than it will be rarely possible to make your appointment. So try from different Mobile at a same time together but not from separate place. If you try from separate places, the same appointment can be booked multiple times which will interfere the HOTLINE Database. Accidentally, if you make multiple appointment for a single patient, it is your responsibility to re-call in HOTLINE and inform them that you did.


Read More About Prof. Dr. M. Amjad Hossain